Chordoma

Disease database

Chordoma is a rare type of cancer that develops in the bones of the skull base and spine. It arises from remnants of the notochord, a structure that is present during early embryonic development. Chordomas are slow-growing tumors that can cause a range of symptoms depending on their location. In this article, we will explore the various symptoms associated with chordoma and discuss potential treatment options.

Back Pain

One of the most common symptoms of chordoma is back pain. This pain can be persistent and may worsen over time. It is often localized to the affected area and can be accompanied by tenderness or swelling. If you experience unexplained back pain that does not improve with rest or over-the-counter pain medications, it is important to consult a healthcare professional for further evaluation.

Headache

Headaches can also be a symptom of chordoma, particularly when the tumor is located in the skull base. These headaches may be severe and persistent, and they may worsen with certain activities such as bending over or straining. If you experience frequent or severe headaches, it is important to seek medical attention to determine the underlying cause.

Difficulty Swallowing

Chordomas located in the skull base or spine can sometimes cause difficulty swallowing. This can manifest as a feeling of food getting stuck in the throat or chest, pain or discomfort while swallowing, or a sensation of choking. If you experience persistent difficulty swallowing, it is important to consult a healthcare professional for further evaluation.

Changes in Bladder or Bowel Function

In some cases, chordomas can affect the nerves that control bladder and bowel function. This can lead to changes such as urinary or fecal incontinence, difficulty initiating urination or bowel movements, or a loss of sensation in the pelvic area. If you notice any changes in your bladder or bowel function, it is important to seek medical attention for proper evaluation and management.

Weakness or Numbness in the Arms or Legs

Chordomas located in the spine can compress the spinal cord or nerve roots, leading to weakness or numbness in the arms or legs. This can result in difficulty walking, loss of coordination, or a decreased ability to perform fine motor tasks. If you experience persistent weakness or numbness in your extremities, it is important to consult a healthcare professional for further evaluation.

Fatigue

Fatigue is a common symptom in many types of cancer, including chordoma. It can be caused by the body’s immune response to the tumor, as well as the physical and emotional toll of the disease. If you experience persistent fatigue that does not improve with rest, it is important to discuss it with your healthcare provider.

Weight Loss and Loss of Appetite

Unexplained weight loss and loss of appetite can be symptoms of chordoma. These symptoms may be caused by the body’s increased energy demands as it fights the tumor, as well as the effects of the tumor on the digestive system. If you experience significant weight loss or a loss of appetite, it is important to consult a healthcare professional for further evaluation.

Vision Changes

Chordomas located in the skull base can sometimes affect the optic nerves or other structures involved in vision. This can lead to changes such as blurred vision, double vision, or a loss of peripheral vision. If you experience any changes in your vision, it is important to seek medical attention for proper evaluation and management.

Hearing Loss or Ringing in the Ears

Chordomas located in the skull base can also affect the structures involved in hearing. This can result in hearing loss or a persistent ringing or buzzing sound in the ears, known as tinnitus. If you experience any changes in your hearing or persistent tinnitus, it is important to consult a healthcare professional for further evaluation.

Bone Pain or Tenderness

Chordomas can cause bone pain or tenderness in the affected area. This pain may be dull or achy and can worsen with movement or pressure. If you experience unexplained bone pain or tenderness, it is important to seek medical attention for proper evaluation and management.

Swelling or Lump in the Affected Area

In some cases, chordomas can cause swelling or the formation of a lump in the affected area. This can be due to the growth of the tumor or the body’s immune response to it. If you notice any swelling or the presence of a lump, it is important to consult a healthcare professional for further evaluation.

Treatment Options

Chordoma is a challenging disease to treat, and the optimal treatment approach depends on various factors such as the location and size of the tumor, as well as the overall health of the patient. Treatment options for chordoma may include:

  • Surgery: Surgical removal of the tumor is often the primary treatment for chordoma. However, due to the complex nature of the disease, complete removal of the tumor may not always be possible.
  • Radiation Therapy: Radiation therapy may be used before or after surgery to target any remaining tumor cells and reduce the risk of recurrence.
  • Targeted Therapy: Targeted therapies are medications that specifically target the genetic mutations or molecular pathways involved in chordoma. These therapies are still being studied and may be used in combination with other treatment modalities.
  • Supportive Care: Supportive care measures such as pain management, physical therapy, and psychological support can help improve the quality of life for individuals with chordoma.

It is important to consult with a multidisciplinary team of healthcare professionals who specialize in the treatment of chordoma to develop an individualized treatment plan.

In conclusion, chordoma is a rare type of cancer that can cause a range of symptoms depending on its location. If you experience any of the symptoms mentioned in this article, it is important to seek medical attention for proper evaluation and management. While chordoma can be challenging to treat, there are various treatment options available that can help improve outcomes and quality of life for individuals with this disease.

Haroon Rashid, MD
Rate author
Urgent Care Center of Arlington, VA
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