What causes skin blisters and how should I treat them?

Symptom Database

Have you ever experienced the discomfort of skin blisters? These small, fluid-filled pockets that form on the surface of the skin can be quite bothersome. Whether caused by friction, burns, or underlying medical conditions, understanding the causes and knowing how to treat and prevent skin blisters is essential for maintaining healthy skin. In this article, we will explore the various causes of skin blisters, effective treatment options, and preventive measures to keep your skin blister-free.

Causes of Skin Blisters

Skin blisters can occur due to a variety of reasons. Understanding the underlying cause is crucial in determining the appropriate treatment. Here are some common causes of skin blisters:


One of the most common causes of skin blisters is friction. When the skin rubs against a rough surface or another part of the body, it can lead to the formation of blisters. This often happens when wearing ill-fitting shoes or engaging in activities that involve repetitive motion, such as running or playing sports.


Burns, whether caused by heat, chemicals, or radiation, can result in skin blisters. The severity of the burn will determine the size and intensity of the blisters. It is important to seek immediate medical attention for severe burns to prevent infection and promote proper healing.

Medical Conditions

Some medical conditions can also cause skin blisters. Conditions such as eczema, dermatitis herpetiformis, and pemphigus can lead to the formation of blisters. These conditions require specialized medical treatment to manage the underlying cause and alleviate symptoms.

Treatment for Skin Blisters

When it comes to treating skin blisters, it is important to consider the cause and severity of the blister. Here are some effective treatment options:

Leave Intact

In most cases, it is best to leave the blister intact. The fluid inside acts as a natural barrier against infection and aids in the healing process. However, if the blister is causing significant pain or discomfort, it may be necessary to drain it.


If you decide to drain the blister, it is crucial to do so safely to prevent infection. Start by cleaning the area with mild soap and water. Then, sterilize a needle or pin by holding it over a flame or rubbing alcohol. Gently puncture the edge of the blister and allow the fluid to drain. Apply an antibiotic ointment and cover the blister with a sterile bandage.

Protective Measures

Protecting the blistered area is essential for proper healing. Use a cushioned bandage or moleskin to reduce friction and pressure on the blister. This will help prevent further irritation and allow the blister to heal more quickly.

Prevention of Skin Blisters

Preventing skin blisters is often easier than treating them. By taking a few preventive measures, you can minimize the risk of developing blisters. Here are some tips to keep your skin blister-free:

Proper Footwear

Wearing well-fitting shoes that provide adequate support and cushioning can help prevent blisters on the feet. Avoid shoes that are too tight or have rough seams that can rub against the skin.

Moisture Control

Excessive moisture can increase the likelihood of blisters. Keep your skin dry by wearing moisture-wicking socks and using talcum powder or antiperspirants in areas prone to sweating.

Protective Gear

If you engage in activities that involve repetitive motion or friction, such as running or playing sports, make sure to wear appropriate protective gear. This can include gloves, padding, or specialized clothing that reduces friction and pressure on the skin.

Remedies for Skin Blisters

In addition to medical treatments and preventive measures, there are several home remedies that can help alleviate the discomfort of skin blisters. Here are some remedies you can try:

Aloe Vera

Aloe vera gel has soothing properties that can help reduce pain and inflammation associated with blisters. Apply a small amount of aloe vera gel directly to the blister and let it dry. Repeat several times a day for relief.

Tea Tree Oil

Tea tree oil is known for its antibacterial properties. Dilute a few drops of tea tree oil with a carrier oil, such as coconut oil, and apply it to the blister. This can help prevent infection and promote healing.

Calendula Cream

Calendula cream, derived from marigold flowers, has anti-inflammatory and healing properties. Apply a thin layer of calendula cream to the blistered area to soothe the skin and aid in healing.


Skin blisters can be uncomfortable and inconvenient, but with the right knowledge and treatment, they can be effectively managed. Understanding the causes, implementing preventive measures, and utilizing appropriate treatment options can help you keep your skin blister-free. Remember to consult a healthcare professional if you have severe or recurring blisters, as they may be a symptom of an underlying medical condition. By taking care of your skin and being proactive, you can minimize the occurrence of skin blisters and maintain healthy, happy skin.

Haroon Rashid, MD
Rate author
Urgent Care Center of Arlington, VA
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