What causes white patches on skin or mouth and how to treat them?

Symptom Database

White patches on the skin or mouth can be a cause of concern for many individuals. This skin discoloration, also known as vitiligo, hypopigmentation, or depigmentation, is a common skin condition that affects people of all ages and ethnicities. Understanding the causes of white patches and knowing how to treat them can help individuals manage this pigmentation disorder effectively.

What are white patches?

White patches, also referred to as skin patches or white spots, occur when the cells responsible for producing melanin, the pigment that gives color to the skin, hair, and eyes, are destroyed or stop functioning. This loss of pigmentation results in the appearance of white patches on the affected areas.

Causes of white patches

There are several factors that can contribute to the development of white patches on the skin or mouth:

  • Autoimmune disorders: Conditions such as vitiligo, where the immune system mistakenly attacks and destroys melanocytes, can lead to the formation of white patches.
  • Heredity: Genetic factors can play a role in the development of white patches, as certain genes are associated with an increased risk of developing vitiligo.
  • Environmental triggers: Exposure to certain chemicals, such as phenols or hydroquinone, can cause depigmentation of the skin.
  • Stress: Emotional or physical stress can trigger or worsen the symptoms of vitiligo.
  • Infections: Some infections, such as fungal infections or certain types of bacteria, can lead to the formation of white patches on the skin.

Treating white patches

While there is currently no cure for vitiligo or other forms of hypopigmentation, there are various treatment options available to manage the condition and improve the appearance of white patches:

Topical treatments

Topical corticosteroids: These medications can help reduce inflammation and repigment the affected areas. They are often prescribed for mild to moderate cases of vitiligo.

Topical calcineurin inhibitors: These medications work by suppressing the immune system and can be used as an alternative to corticosteroids.

Topical psoralen plus ultraviolet A (PUVA): This treatment involves applying a psoralen medication to the skin, followed by exposure to UVA light. It stimulates repigmentation and is often used for more extensive cases of vitiligo.

Phototherapy

Narrowband ultraviolet B (NB-UVB) therapy: This treatment involves exposing the affected skin to a specific wavelength of UVB light. It can help stimulate melanocyte activity and promote repigmentation.

Excimer laser: This targeted laser therapy delivers a high-intensity beam of UVB light to the affected areas, promoting repigmentation.

Surgical options

Autologous skin grafting: This procedure involves taking healthy skin from one part of the body and transplanting it to the affected areas. It is often used for small, localized patches of vitiligo.

Micropigmentation: Also known as tattooing, this technique involves implanting pigment into the skin to match the surrounding areas. It can be used to camouflage white patches and create a more even skin tone.

Managing oral lesions

In addition to white patches on the skin, some individuals may also experience oral lesions associated with vitiligo. These can appear as white patches or spots on the inside of the mouth, lips, or tongue. While there is no specific treatment for oral lesions caused by vitiligo, the following measures can help manage the symptoms:

  • Good oral hygiene: Maintaining proper oral hygiene practices, such as regular brushing and flossing, can help prevent infections and promote overall oral health.
  • Moisturizing agents: Using moisturizing mouthwashes or gels can help alleviate dryness and discomfort associated with oral lesions.
  • Protective measures: Avoiding spicy or acidic foods, as well as tobacco and alcohol, can help prevent irritation and further damage to the oral tissues.

It is important to note that the effectiveness of treatment options may vary depending on the individual and the extent of the condition. Consulting with a dermatologist or healthcare professional is crucial to determine the most suitable treatment plan.

In conclusion, white patches on the skin or mouth can be a result of various factors, including autoimmune disorders, heredity, environmental triggers, stress, or infections. While there is no cure for vitiligo or other forms of hypopigmentation, there are several treatment options available to manage the condition and improve the appearance of white patches. Additionally, individuals experiencing oral lesions associated with vitiligo can adopt certain measures to alleviate discomfort and maintain oral health. Seeking professional advice is essential to determine the most appropriate treatment approach for each individual.

Haroon Rashid, MD
Rate author
Urgent Care Center of Arlington, VA