Peyronie’s Disease

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Peyronie’s Disease is a condition that affects the penis, causing curvature, pain or discomfort during an erection, erectile dysfunction, and other related symptoms. It is characterized by the development of a lump or plaque on the penis, which can lead to shortening of the penis and difficulty with sexual intercourse. In this article, we will explore the causes, symptoms, and treatment options for Peyronie’s Disease, as well as provide valuable insights and tips for managing this condition.

Understanding Peyronie’s Disease

Peyronie’s Disease is named after François Gigot de la Peyronie, a French surgeon who first described the condition in 1743. It is believed to be caused by the formation of scar tissue, known as plaque, within the penis. This plaque can develop on the top or bottom of the penis, causing it to bend or curve during an erection.

While the exact cause of Peyronie’s Disease is unknown, it is believed to be a result of trauma or injury to the penis. This can occur during sexual activity, such as vigorous intercourse or masturbation, or due to an accident or injury. Some men may be more prone to developing Peyronie’s Disease due to genetic factors or certain medical conditions.

Recognizing the Symptoms

The most common symptom of Peyronie’s Disease is curvature of the penis. This curvature can vary in severity, ranging from a slight bend to a more pronounced curve. In addition to curvature, other symptoms may include:

  • Pain or discomfort during an erection
  • Erectile dysfunction
  • A lump or plaque on the penis
  • Shortening of the penis
  • Difficulty with sexual intercourse

If you experience any of these symptoms, it is important to consult with a healthcare professional for an accurate diagnosis and appropriate treatment options.

Diagnosing Peyronie’s Disease

To diagnose Peyronie’s Disease, a healthcare professional will typically perform a physical examination and review your medical history. They may also order additional tests, such as an ultrasound or X-ray, to assess the extent of the curvature and the presence of plaque.

It is important to note that Peyronie’s Disease can sometimes be mistaken for other conditions, such as erectile dysfunction or a penile fracture. Therefore, an accurate diagnosis is crucial for determining the most effective treatment approach.

Treatment Options

While there is no known cure for Peyronie’s Disease, there are several treatment options available to manage the symptoms and improve sexual function. The choice of treatment will depend on the severity of the symptoms and the impact on your quality of life.

Non-Surgical Treatments

Non-surgical treatments are often the first line of defense against Peyronie’s Disease. These may include:

  • Medications: Certain medications, such as collagenase clostridium histolyticum, may be prescribed to help break down the plaque and reduce curvature.
  • Penile traction devices: These devices apply gentle traction to the penis, helping to straighten the curvature over time.
  • Verapamil injections: Verapamil, a medication commonly used to treat high blood pressure, can be injected directly into the plaque to help soften and reduce its size.

Surgical Treatments

If non-surgical treatments are ineffective or the curvature is severe, surgical intervention may be necessary. Surgical options for Peyronie’s Disease include:

  • Plication: This procedure involves suturing the unaffected side of the penis to reduce curvature.
  • Grafting: In cases of severe curvature or penile shortening, a graft may be used to lengthen the penis and improve its appearance.
  • Penile prosthesis: In some cases, a penile prosthesis may be implanted to restore erectile function and correct curvature.

It is important to discuss the potential risks and benefits of each treatment option with your healthcare professional to determine the best course of action for your specific situation.

Living with Peyronie’s Disease

While Peyronie’s Disease can have a significant impact on a man’s physical and emotional well-being, there are strategies that can help improve quality of life:

  • Open communication: Discussing your condition with your partner can help alleviate anxiety and maintain a healthy sexual relationship.
  • Seek support: Joining a support group or seeking counseling can provide emotional support and valuable insights from others living with Peyronie’s Disease.
  • Explore alternative sexual activities: Experimenting with different sexual positions or activities that minimize discomfort can help maintain intimacy and pleasure.

Remember, Peyronie’s Disease is a manageable condition, and with the right treatment and support, you can continue to enjoy a fulfilling sex life.


Peyronie’s Disease is a condition that can cause curvature of the penis, pain or discomfort during an erection, erectile dysfunction, a lump or plaque on the penis, shortening of the penis, and difficulty with sexual intercourse. While there is no known cure, there are various treatment options available to manage the symptoms and improve quality of life. It is important to consult with a healthcare professional for an accurate diagnosis and personalized treatment plan. By seeking appropriate care and support, individuals with Peyronie’s Disease can lead fulfilling and satisfying lives.

Haroon Rashid, MD
Rate author
Urgent Care Center of Arlington, VA
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